Dr. Platt narrates a personal slideshow from his Summer research trip to South Africa and Ethiopia. Click the picture to watch!
Platt Lab Mission: To fuse engineering, cell biology, and physiology to understand how cells sense, respond, and remodel their immediate mechanical and biochemical environments for repair and regeneration in health and disease, then to translate that knowledge to clinics domestically and internationally to address global health disparities.
ANNOUNCEMENTS and NEWS:
Platt Lab's Georgia Tech BME team won FIRST PLACE at the 35th Annual Sickle Cell 4K Walk/ 7K Run last weekend!!
Thanks to all who joined us for the event, great way to support the Sickle Cell Foundation of Georgia that advocates tirelessly for its clients to help those with sickle cell disease live healthier lives.
Team prize and several individual winners in age group categories for race times.
Click to see more photos from the event. (April 2014)
Congratulations to Catera Wilder for selection to the inaugural class of BEST scholars!
The Atlanta Broadening Experiences in Scientific Training (BEST) Program is a new NIH Common Fund program that is centered around
exposing pre-doctoral and post-doctoral scientists at Georgia Tech and Emory University to different career opportunities outside of academia. The trainees will be exposed to a breadth and depth of biomedical research career opportunities including law and business, scientific communications,
STEM education, technology transfer and intellectual property, non-tenured track research, and industrial science.
Click for more information.
Congratulations to Daniel Clough and Joel Chic for graduating from Georgia Tech with their Bachelor's degree in Biomedical Engineering! (December 14, 2014)
Platt Lab Takes over Cape Town, South Africa for the International Proteolysis Society Meeting!
8th General meeting of the International Proteolysis Society Meeting was held in October 2013 in Cape Town, South Africa. Platt lab members Philip Keegan, Keon-young Park, Ivana Parker, Catera Wilder, Kristi Porter, and Binbin Chen attended and presented our research
on involvement of cathepsins in sickle cell disease, HIV and cardiovascular disease, endometriosis, and breast cancer.
We were also sure to share our work on multiplex cathepsin zymography technology developed in the lab and our new research thrust of cathepsin cannibalism and proteolytic networks and feedback.
Great to share with our brothers and sisters in the Proteolysis field, great networking, great science, and of course, great wine and safaris (Hey, the conference was held on a South African vineyard!)
2 talks, 3 posters, and 4 awards!
Click here to see more pictures from the trip
Scientists Work to Engineer an Injectable Therapy for Rotator Cuff Injuries - R01 Awarded with Dr. Johnna Temenoff!
"Normally people focus on treating tendon injuries after the tear has occurred, but we're focusing on a much earlier stage in the disease" said Johnna Temenoff,
an associate professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.
"This is the first time that an injectable therapy specifically designed to interact with tissue at an early disease state has been attempted for this particular tendon injury."
Click to read more
Temenoffs work is supported by a $1 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) for five years of research, which began in September 2013.
Dr. Platt is a co-investigator to develop methods to inhibit cathepsins and other proteases that contribute to tendinopathy. Exciting new work and glad to continue the collaboration with NIH funding! (September 2013)
BMES Annual Meeting 2013 in Seattle
Graduate student Ivana Parker presented her work in a talk on HIV and Cardiovascular Disease, Undergraduate student Monet Roberts presented a poster on her contributions to HIV antiretroviral medication and cardiovascular disease, Undergraduate student Gabbie Nortey presented work from her summer at WPI,
and Undergraduate student Daniel Clough presented his work on Developing Cellular Models of Sickle Cell Trait. Dr. Platt hosted the BMES Celebration of Minorities in BME luncheon with special guest speaker Dr. Aida Habtezion from Stanford University where she shared a powerful story of loving science and achieving
against many odds by keeping family first and doing excellent science. (September 2013)
Congratulations to Meghan Ferrall for being selected for the Tau Beta Pi Fellowship! She has been a committed member and leader since her undergraduate days and continues onward.
Congratulations to Keon-Young Park for being selected for the SIRE-HHMI Graduate Fellowship for the 2013-2014 academic year!
Scholarly Inquiry and Research at Emory (SIRE) SIRE promotes undergraduate research projects through grants,
faculty-student research partnerships, and summer research stipends, offering advantages to both students and faculty. These undergraduate researchers assist faculty in accomplishing ambitious research and allow faculty to work with self-motivated,
developing scholars. The fellowship is co-funded by the Laney Graduate School, the Deans Office of Emory College of Arts and Sciences, and the Howard Hughes Medical Institute (HHMI).
New Platt Lab HIV and Cardiovascular Disease publications out now in collaboration with Dr. Rudy Gleason and Dr. Roy Sutliff!
Endothelial dysfunction, arterial stiffening, and intima-media thickening in large arteries from HIV-1 transgenic mice.
Laura Hansen, Ivana Parker, Roy L. Sutliff, Manu O. Platt, and Rudy L. Gleason Jr.
Annals of Biomedical Engineering. 2013 Apr;41(4):682-93.
Azidothymidine (AZT) leads to arterial stiffening and intima-media thickening in mice.
Laura Hansen, Ivana Parker, LaDeidra Monet Roberts, Roy L. Sutliff, Manu O. Platt, and Rudy L. Gleason Jr.
Journal of Biomechanics. 2013 May 31;46(9):1540-7.
Congratulations to all!!
BMES Outreach event featured on National Public Radio!
Interview with Dr. Platt, Dr. Nerem, and Dr. Jo and students.
High school hands-on demonstrations were led by Georgia Tech BME Undergrads, BME graduate students, and EBICS collaborating graduate students with local high school students from
B.E.S.T. Academy, Coretta Scott King Young Women's Leadership Academy, Benjamin E. Mays High School, Wheeler High School, South Atlanta High School, and several students from South Carolina sponsored by Clemson University's BMES Chapter.
Be sure to click LISTEN
Congratulations to Platt Lab undergrad Binbin Chen for winning Best Poster Award at the
Out to Innovate 2012 Conference at Ohio State University in Columbus, OH!
Binbin was presenting his work "Quantitative Toolbox to Measure Osteoclast and Cathepsin K Activity in Orthopedic Tissues" that describes new assays and technologies we have been developing to quantify osteoclast differentiation in studies of bone loss in disease.
Ivana Kennedy working on HIV and cardiovascular disease in Addis Ababa, Ethiopia
Ivana has been working at Black Lion Hospital in Addis Ababa since the end of April to study the effects of anti-retrovirals on cardiovascular disease markers in people living with HIV.
This is a part of our collaborative project with Dr. Rudy Gleason who has been in Addis Ababa since October as a Fulbright Fellow and Dr. Roy Sutliff at Emory as a part of our CNIHR grant.
Click here to see pictures of Dr. Platt's trip over to help set up a new assay and bring new supplies.
Ivana will be back at the end of June after being there for two months.
Global translational research! Trying to make a difference even when the resources are limited.
Binbin Chen wins Goldwater Scholarship!
Platt lab undergrad Binbin Chen selected as a recipient of the prestigious Barry M. Goldwater Scholarship, the premier academic award given to mathematics, science and engineering undergraduates.
Congratulations to Philip Keegan for being selected for the Whitaker International Summer Program Grant! He will go to Johannesburg, South Africa to work at the University of Witswatersrand to continue studies on HIV and cardiovascular disease.
This grant is funded by Whitaker International Program.
Congratulations to undergraduate researcher LaDeidra Monet Roberts for being selected for the Whitaker Undergraduate Program Award for Fall 2012 for her proposed study in France this coming fall!
This Scholarship is funded by Whitaker International Program and the Institute of International Education
Platt Lab with a few affiliates, including Dr. Platt's mom, participated in the 33rd Annual Sickle Cell Road Race
Saturday April 14, 2012
Click here for pictures
Platt Lab Dodgeball team takes on Georgia Tech undergraduates!
Team captain and coach Daniel Clough sees improvement week to week, and promises a win with new strategy.
Dr. Platt's recent trip to Johannesburg, Africa to test HIV blood for biomarkers of adherence to antiretroviral drug regimens featured on College of Engineering homepage.
Congratulations to Binbin Chen and Sindhuja Surapaneni for being selected for Georgia Tech
President's Undergraduate Research Awards for Spring Semester! (Nov 2011)
Congratulations to Dr. Platt for being 1 of 5 selected for the Keystone Symposia Fellows Program
This highly unique, research-driven, diversity-centered program educates early career scientists regarding the inner workings of the life sciences community and provides a venue for high-level interaction with established and leading scientists nationally and globally. The Fellows Program provides context, understanding and insight regarding the development of high-powered research meetings, utilizing shadowing experiences with scientist organizers and key Keystone Symposia staff members. These experiences allow for learning how the research agenda is set, how to engage in high-level discourse on research topics and how to broaden perspectives in life science research. (Nov 2011)
New Platt Lab publication accepted into Archives of Biochemistry and Biophysics!
"Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues" Catera L. Wilder, Keon-Young Park, Philip M. Keegan, Manu O. Platt (Nov 2011)
Welcome new faces to Platt Lab: Dr. Idy Akinsanmi, Dr. Usman Saeed, Terrance White, and Saranya Karthikeyan. Check them out on the People page
New Platt Lab publication accepted in collaboration with the Segura Lab at UCLA in Integrative Biology!
"VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF." Sean M. Anderson, Bhupinder Shergill, Zachary T. Barry, Eleana Manousiouthakis, Tom T. Chen, Elliot Botvinick, Manu O. Platt, M. Luisa Iruela-Arispe, Tatiana Segura (July 2011)
New Platt Lab publication accepted into Journal of Translational Medicine!
"Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer." Binbin Chen and Manu O. Platt (July 2011)
Congratulations to Jerald Dumas for being awarded the FIRST Postdoctoral Fellowship!! (May 2011)
Return of the Platt Lab FELLOWSHIP EXPLOSION!!
Congratulations to Catera Wilder for being awarded an
NSF Graduate Research
Fellowship! AND a Ford Foundation Fellowship
That makes 5 out of 5 NSF Fellows
for the Platt Lab. AMAZING! (April
Pediatric Stroke Prediction: $1.5M Grant Funds Research Aimed at
Reducing Strokes in Children with Sickle Cell Disease (Oct 2010)
March 11, 2014