Jin Sou
Ph.D. Student
Biomedical Engineering

Aortic Arch

Magnetic resonance imaging (MRI) and computational fluid dynamics (CFD) have been combined to investigate flow patterns in the aorta. The vascular model was reconstructed from MR slices in vivo. MR phase velocity supplied boundary flow conditions and wall movement information to the simulation. The CFD results were verified by MRI. The animation below shows the movement of the aortic arch modeled over time.

Aorta Model Constructed from MR Slices

 

Investigation of Blood Flow Patterns and Hemodynamics in Human Ascending Aorta and Coronary Arteries Using MRI, CT and CFD

Hemodynamic factors play a role in atherogenesis. My research focused on the flow patterns and WSS in human aorta and coronary arteries using CFD combined with clinical imaging in vivo. One contribution of the research was certification that the oscillatory aortic motion caused by the beating heart is a main factor to produce the right-hand helical flow patterns in the ascending aorta. Another contribution demonstrated that a pair of axial vortexes with different rotating directions exists in the entrance segments of the right and left coronary arteries during systole and early diastole. The vortexes caused by the flow in the aorta root produce asymmetrical wall shear stress (WSS) distributions in the entry regions of coronary arteries.

Helical flow patterns in the human ascending aorta.

WSS distribution in the human left coronary artery and its open state (lower). The unit color bar is dyne per square centimeter.

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